FIG 2.
Differential motor impairment in mice following intramuscular injection. (A) Motor impairment was scored daily for 14 days post-intramuscular challenges with the indicated EV-D68 strains. None of the mice infected with US/TN or VR1197 developed signs of paralysis, whereas 100% of mice infected with US/MO/47 developed paralysis. Error bars represent standard error of the mean (SEM). (B and C) Viral titers from muscle and spinal cord titers were determined by TCID50 assay on samples taken at 0, 2, 4, and 6 days post-intramuscular infection. Error bars represent standard deviation (SD).