FIGURE 3.

Genome browser snapshots (as in Fig. 1B) of three arbitrarily selected regions around the transcription start sites of genes, in which misincorporations enriched upon IP with respect to IP + Dimroth were not identified. In all cases, misincorporations can be viewed both at the position marked by the black lines, but often also in nearby positions. In the left and right panels the highlighted position does not contain an A. In all cases, the mismatches with respect to the genome occur at the very first base of the read (in some cases they encompass the first two or three bases of the read). The misincorporations are present both in IP and IP + Dimroth treated samples.