Table 3.
BP response to dietary sodium intervention according to rs6967221 genotype
Low-sodium intervention | High-sodium intervention | ||||
---|---|---|---|---|---|
BP response | Genotype | Absolute change (95% CI) | P value for additive model | Absolute change (95% CI) | P value for additive model |
SBP | CC | −5.60 (−5.97, −5.22) | 0.27 | 5.03 (4.71, 5.36) | 4.51 × 10−4 |
CT | −5.07 (−5.85, −4.29) | 4.20 (3.54, 4.85) | |||
TT | −5.85 (−7.78, −3.92) | 0.56 (−1.08, 2.20) | |||
DBP | CC | −2.81 (−3.12, −2.50) | 0.89 | 2.00 (1.68, 2.32) | 0.41 |
CT | −2.93 (−3.63, −2.24) | 1.85 (1.21, 2.49) | |||
TT | −2.27 (−4.92, 0.38) | 0.60 (−2.11, 3.32) | |||
MAP | CC | −3.74 (−4.03, −3.44) | 0.75 | 3.01 (2.72, 3.30) | 5.50 × 10−2 |
CT | −3.65 (−4.31, −2.99) | 2.64 (2.07, 3.21) | |||
TT | −3.46 (−5.59, −1.34) | 0.60 (−1.50, 2.69) |
Abbreviations: CI, confidence interval; DBP, diastolic blood pressure; MAP, mean arterial pressure; SBP, systolic blood pressure.