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. 2018 Oct 16;18:982. doi: 10.1186/s12885-018-4888-2

Table 2.

Univariate and multivariate analyses of progression-free survival

Number of patients Univariate Multivariate
Parameter Yes No HR 95% CIs P value HR 95% CIs P value
Age < 58 yo 23/51 28/51 2.440 1.120–5.316 0.0248 0.315 0.074–1.467 0.1367
Estrogen receptor positive (vs. negative) 23/51 28/51 1.198 0.555–2.588 0.6448
Progesterone receptor positive (vs. negative) 11/51 40/51 1.177 0.456–3.040 0.7361
HER2 3+ 40/51 11/51 1.421 0.558–3.618 0.5431
Non-visceral metastases (vs. visceral) 32/51 19/51 0.926 0.429–1.996 0.8441
Eribulin (vs. Nab-PTX) 30/51 21/30 1.593 0.751–3.378 0.2249
Prior treatment < 3 line 30/51 21/30 0.401 0.185–0.870 0.0208 0.528 0.234–1.157 0.1106
Absolute lymphocyte count ≥ 1000/uL 37/51 14/51 0.308 0.133–0.714 0.0061 0.735 0.284–1.770 0.4977
Absolute lymphocyte count ≥ 1500/uL 19/51 32/51 0.372 0.174–0.796 0.0108 0.296 0.098–0.794 0.0150
Neutrophil to lymphocyte ratio > 2 31/51 20/51 2.109 0.985–4.516 0.0548
Platelet to lymphocyte ratio > 150 31/51 20/51 2.038 0.962–4.318 0.0632