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. 2018 Aug 20;124:21–30. doi: 10.1016/j.freeradbiomed.2018.05.078

Table 3.

Correlation coefficients (r) for relationships between relative abundances of selected taxonomic units of saliva microbiome (% of total bacteria) and plasma nitrate ([NO3-]) and nitrite ([NO2-]); diastolic (DBP), systolic (SBP) and mean arterial (MAP) blood pressure; and pulse wave velocity (PWV) across placebo and nitrate conditions. Microbiome data were not available for one young male subject and PWV data were not available for one older male subject, such that [NO3-], [NO2-] and BP correlations are for n = 34 and PWV correlations are for n = 32.

[NO3-] (μM) [NO2-] (nM) DBP (mmHg) SBP (mmHg) MAP (mmHg) PWV (m/s)
Actinobacteria Actinomycetales (order) 0.25 0.09 − 0.01 − 0.09 − 0.05 0.06
Micrococcales (order) 0.37* 0.23 − 0.03 0.02 0.00 0.48**
Rothia (genus) 0.45** 0.30# 0.04 0.03 0.04 0.45*
Rothia mucilaginosa 0.46** 0.37* 0.06 − 0.03 − 0.01 0.41*
Proteobacteria Neisseria (genus) 0.61** 0.64** 0.02 0.15 0.14 − 0.13
Neisseria meningitidis 0.54** 0.53** − 0.00 0.07 0.08 − 0.23
Campylobacter concisus − 0.26 − 0.17 − 0.17 0.08 0.02 0.42*
Bacteroi-detes Prevotella (genus) − 0.47** − 0.35* 0.11 0.21 0.18 − 0.18
Prevotella melaninogenica − 0.47** − 0.35* 0.06 0.17 0.12 − 0.09
Firmicutes Veillonella (genus) − 0.62** − 0.50** − 0.10 − 0.01 − 0.22 − 0.07
Veillonella parvula − 0.60** − 0.49** − 0.10 − 0.03 − 0.23 − 0.08
Fuso-bacteria Fusobacterium nucleatum subsp. nucleatum − 0.28 − 0.18 0.00 0.08 0.05 − 0.10
Fusobacterium nucleatum subsp. vincentii − 0.16 − 0.01 − 0.03 0.12 0.07 − 0.17

DBP=diastolic blood pressure; SBP= systolic blood pressure; MAP= mean arterial pressure; PWV= pulse wave velocity.

**

P < 0.01.

*

P < 0.05.

#

P < 0.10.