Fig. 3.

Effects of ginseng seed oil (GSO) on high-fat diet (HFD)-induced changes in C57BL/6J mice. (A, B) Weekly body weight change was measured, and the body weight gain was calculated. (C) Serum lipid profiles including total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were measured. (D) The ratio of LDL-C over HDL-C was calculated. (E, F) Serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were measured as liver toxicity parameters. *p < 0.05; **p < 0.01; ***p < 0.001 versus HFD. MET, metformin; RD, regular diet.