Table 2.
Study characteristics.
| Author (year) | Research type | Population | Study length (years) | C | MD | O | DM | OSA | ||
|---|---|---|---|---|---|---|---|---|---|---|
| Total | Control (asthma-only) | Comorbid condition | ||||||||
| Kendzerska et al. [8]∗ | Retrospective cohort | — | — | — | 10 | M | ||||
| Baarnes et al. [9] | Retrospective cohort | 57,053 | 1,845 | 662 | 4 | M | ||||
| Yamauchi et al. [10] | Retrospective cohort | 30,405 | 19,865 | 6,279 | 3 | M and ER | ||||
| Harada et al. [11] | Retrospective | 650 | 474 | 176 | 12 | M | ||||
| Becerra et al. [12] | Inpatient sample study | 179, 789 | 136,118 | 8,189 | 3 | LOS | ||||
| Vuillermin et al. [13] | Cross-sectional analysis | 615 | 410 | 205 | 1 | ER | ||||
| Ahmedani et al. [14] | Prospective follow-up study | 568 | N/A | 187 | 1 | ER | ||||
| Wiesenthal et al. [15] | Prospective follow-up study | 460 | 227 | 233 | 3 | ER | ||||
| Hsiao et al. [16] | Retrospective cohort | 17,725 | 766 | 3,545 | 13 | ER | ||||
Description of results from each selected article regarding the significant differences in hospital/emergency room (ER) visits, mortality (M), and hospital length of stay (LOS) in patient due to the chronic disease comorbidity compared to the asthma-only control. C, COPD/asthma comorbidity; MD, mental disorder/asthma comorbidity; O, obesity/asthma comorbidity; D , diabetes mellitus/asthma comorbidity; OSA , obstructive sleep apnea. ∗This paper utilized a population health administrative data for all individuals living in Ontario, Canada (population of approximately 13 million in 2010) that are over the age of 35. ∗∗No articles were found that discussed the clinical impacts of either hypertension-asthma, myocardial ischemia-asthma, or rhinitis/sinusitis-asthma comorbidity.