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. 2018 Oct 15;19:162. doi: 10.1186/s13059-018-1490-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — General patterns in the data. a Normalized log₂(CPM) expression measurements for all genes projected onto the axes of the first two PCs. Color indicates day. Shape represents species. PC1 is highly correlated with differentiation day (r = 0.92). PC2 is highly correlated with species (r = 0.93). b Box plots of normalized expression values for genes with known roles in endoderm development