Table 4.
Predictive value of tests by pairwise comparisons for progression to tuberculosis
TST-5 | TST-10 | TST-15 | T-SPOT.TB | QuantiFERON-TB Gold In-Tube | |
---|---|---|---|---|---|
TST-5 | .. | 1·25 (1·15–1·36; <0·0001) | 1·64 (1·44–1·87; <0·0001) | 1·99 (1·68–2·34; <0·0001) | 1·52 (1·26–1·83; <0·0001) |
TST-10 | .. | .. | 1·31 (1·617–1·47; <0·0001) | 1·59 (1·34–1·88; <0·0001) | 1·21 (1·01–1·46; 0·041) |
TST-15 | .. | .. | .. | 1·21 (1·01–1·43; 0·037) | 0·93 (0·76–1·13; 0·453) |
T-SPOT.TB | .. | .. | .. | .. | 0·77 (0·66–0·89; 0·0003) |
Values indicate the ratio of test positivity rates (with 95% CI and p values) in participants who progressed to active tuberculosis compared with those who did not comparing test A (horizontally across table) with test B (vertically up table). A value above 1 indicates a positive result on test A is a stronger predictor of progression to tuberculosis than a positive result on test B. TST=tuberculin skin test. TST-5=TST with threshold ≥5 mm. TST-10=TST with threshold ≥10 mm. TST-15=BCG-dependent definition of TST: ≥15 mm for BCG-vaccinated participant and >5 mm non-vaccinated participant.