Table 5.
Predictive value of tests by pairwise comparisons for no progression to tuberculosis
TST-5 | TST-10 | TST-15 | T-SPOT.TB | QuantiFERON-TB Gold In-Tube | |
---|---|---|---|---|---|
TST-5 | .. | 1·18 (0·86–1·63; 0·300) | 1·35 (0·90–2·01; 0·147) | 1·28 (0·77–2·12; 0·337) | 1·60 (0·97–2·65; 0·065) |
TST-10 | .. | .. | 1·14 (0·86–1·51; 0·368) | 1·08 (0·72–1·62; 0·704) | 1·35 (0·91–2·01; 0·130) |
TST-15 | .. | .. | .. | 0·95 (0·67–1·36; 0·784) | 1·19 (0·84–1·68; 0·319) |
T-SPOT.TB | .. | .. | .. | .. | 1·25 (0·97–1·61; 0·081) |
Values indicate the ratio of test negativity rates (with 95% CI and p values) in participants who progressed to active tuberculosis compared with those who did not comparing test A (horizontally across table) with test B (vertically up table). A value below 1 indicates a negative result on test A is a stronger predictor of no progression to tuberculosis than a negative result on test B. TST=tuberculin skin test. TST-5=TST with threshold ≥5 mm. TST-10=TST with threshold ≥10 mm. TST-15=BCG-dependent definition of TST: ≥15 mm for BCG-vaccinated participant and >5 mm non-vaccinated participant