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. 2018 Sep 28;7:25. doi: 10.1186/s40035-018-0128-6

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Golgi staining identified the effect of AAV-hm-α-syn injections on neuronal morphology. (a and b) Representative photographs of dendritic protrusions in the substantia nigra. A: 20× magnification. B: 100× magnification in oil immersion. (c) Effect of AAV-hm α-syn on spine density. These results indicated that there was a more significant decrease in spine density in several brain regions in rats injected with AAV-hm-α-syn (vs. control, * means p < 0.05). e Representative photographs of dendritic spines in the SN (100× magnification times in oil immersion). d Effect of AAV-hm-α-syn on the total number of intersection points. The results indicated that there was a significant reduction of the total number of intersection points in different brain regions in rats treated by AAV-hm-α-syn (vs. control, * < 0.05). Data are presented as mean ± SD. *P < 0.05, **P < 0.01. f: Representation diagrams about Goligi staining by AAV & control injection