. 2018 Oct 16;15:160. doi: 10.1186/s12985-018-1073-9

Table 2.

Comparative analysis of HCPs present in viruses and ECVs

Protein	MM^a/kDa	UC			HIC						IAC
		UC			E1			E2			IAC
		ECV	MUV	MEV	ECV	MUV	MEV	ECV	MUV	MEV	ECV	MUV
heparan sulphate proteoglycan	469									+
filamin	280	+		+
fibronectin	262	+	+	+	+	+	+	+	+	+
clathrin heavy chain (HC)	192	+		+
vinculin	124	+
integrin α III	117		2D					+			+
integrin α V	116	+	+					+			+
Na⁺/K⁺ ATPase subunit 1	113	+
α-actinin	103	+			+
major vault protein (MVP)	99	+	+			+		+	+		+
transitional endoplasmatic reticulum ATPase (TER ATPase)	89		+		+
integrin β1	88	+	+	+				+	+	+	+	+
heat shock protein 90 (HSP90)	83	+			+			+
protein disulphide-isomerase A4 (PDIA4)	73	+
heat shock protein A5 (HSPA5)	72	+	+
heat shock protein 70 (HSP70)	71	+	+	+				+	+
moesin	68	+	+	2D				+	+	+		+
BSA (precursor)	66	+
galectin-3-binding protein (G3BP)	65							+	+	+
pyruvate kinase	62	+
gamma-glutamyltransferase (GGT)	61							+
glucose-6-phosphate 1-dehydrogenase	59	+
protein disulphide-isomerase A3 (PDIA3)	57	+	2D
aldehyde dehydrogenase	55	+
tubulin β	50	+	+
tubulin α	50	+	+	2D								+
α-enolase	47	+	2D	+
actin	42	+	+	+			+	+	+	+		+
MHC class I antigen	41							+
annexins A1,A2,A4,A5	39	+	+	+	+	+	+	+	+	+	+	+
aldolase reductase	36	+	2D
glyceraldehyde 3-phosphate dehydrogenase (GAPDH)	36	+
ribosomal protein 40S SA	33	+
triosephosphate isomerase	31	+	2D	2D
ribosomal protein L7a	30		+
ribosomal protein 40S S4	30	+
clathrin light chain (LC)	27	+
chloride intracellular channel protein	27		+
galectin-3	26		2D					+
CD9, CD81	25									+
ras-related protein Rab 5	24							+
glutathione S-transferase (GST)	23	+	2D
ribosomal protein 40S S5	23	+
heat shock protein β1 (HSPβ1)	23	+	+	2D				+			+
RhoA	22							+
peroxiredoxin	22	+	2D	2D
cyclophilin A (CypA)	18	+	+	+				+	+	+		+
ubiquitin-ribosomal protein S27a	18	+		2D
ribosomal protein 40S S16	16	+	+
ribosomal protein 40S S14	16	+
galectin-1	15	+		2D
profilin-1	15	+
histone H3	15	+	+	+							+	+
histone H2AX	15	+	+	+
β₂-microglobulin	14	+
ribosomal protein 60S L30	13		+
S100-A11	12		2D					+
histone H4	11		+	+							+	+
S100-A10	11							+

^amolecular mass of a monomer is given

2D – indicates that the protein was detected in 2D gel electrophoresis of UC purified MEV (Table 1, sample C and Fig. 1(C)) or MUV (Table 1, sample (C) and Fig. 2(C)), but not when these samples were resolved only by SDS-PAGE (for further information see Additional file 1: Figure S6 & Table S1)