Fig. 2.

Simulation results. A set of replicate RNA-seq samples collected at the same time were shuffled and assigned a time-order. The number of top dynamic genes identified by Trendy was determined using two adjusted R² thresholds of ${\overline{R}}_{g,{\tilde{k}}_g}^2>.5$ and ${\overline{R}}_{g,{\tilde{k}}_g}^2>.8$. Shown in panel a are the number of genes above the ${\overline{R}}_{g,{\tilde{k}}_g}^2$ cutoffs for all combinations of settings for K,N,and mNS (each combination was simulated 300 times over varying point distributions). Panel b contains the number of genes above each cutoff over three various point distribution scenarios (each box contains 2400 simulations over all other varied parameters)