0400068_T1 |
M |
44 |
Metastatic |
No prior chemotherapy |
BRCA2, KRAS |
FOLFIRINOX -- PARP inhibitor (OL) |
0400075_T1 |
F |
58 |
Metastatic |
No prior chemotherapy |
CHEK2, KRAS, gBRCA1
|
FOLFIRINOX -- PARP inhibitor vs. placebo (CT) |
0400078_T1 |
F |
39 |
Metastatic |
GA/JAK inhibitor (CT), FOLFIRINOX |
KRAS, CDKN2A, gBRCA2
|
UBA1 inhibitor (CT) -- PARP inhibitor (OL) |
0400096_T1 |
M |
57 |
Metastatic |
No prior chemotherapy |
KRAS, CDKN2A |
FOLFIRINOX -- GA/Anti-MUC5AC mAb (CT) |
0400097_T1 |
M |
48 |
Metastatic |
No prior chemotherapy |
KRAS |
FOLFIRINOX -- GA -- CHK1/2 inhibitor (CT) |
0400117_T2 |
F |
65 |
Metastatic |
FOLFIRINOX, GA |
KRAS, CDKN2A
|
PI3K/mTOR inhibitor/CDK4/6 inhibitor (CT) |
0400127_T1 |
F |
60 |
Metastatic |
No prior chemotherapy |
KRAS, CDKN2A
|
FOLFIRINOX -- GA -- CDK4/6 inhibitor/MEK1/2 inhibitor (CT) |
0400151_T2 |
F |
61 |
Metastatic |
FOLFIRINOX, GA |
KRAS, CDKN2A |
CDK2/5/9 inhibitor (CT) |
0400165_T1 |
F |
73 |
Metastatic |
FOLFIRINOX |
ERCC2, KRAS |
GA -- Prostaglandin E2 receptor EP4 antagonist (CT) |
0400172_T1 |
M |
58 |
Metastatic |
No prior chemotherapy |
BRAF, CDKN2A |
FOLFIRINOX -- MEK1/2 inhibitor (OL) -- GA -- ERK1/2 inhibitor (SP-IND) |
0400174_T1 |
M |
77 |
Metastatic |
No prior chemotherapy |
ATM (biallelic), KRAS, CDKN2A |
GA -- 5FU/LV/Nal-Iri -- PARP inhibitor (OL) |
0400177_T1 |
F |
64 |
Metastatic |
FOLFOX, 5FU/LV/Nal-Iri, GA |
KRAS, NBN, FANCM
|
PARP inhibitor/CDK1/2/5/9 inhibitor (CT) |
0400197_T1 |
F |
65 |
Metastatic |
FOLFIRINOX, GA |
BRAF, FGFR1 (amplification) |
MEK1/2 inhibitor (OL) -- ERK1/2 inhibitor (SP-IND) |
0400202_T1 |
M |
83 |
Metastatic |
ROS1 inhibitor (CT) |
CDKN2A, ROS1 (translocation)
|
ROS1 inhibitor (OL) -- ROS1 inhibtor (OL) |
0400242_T1 |
F |
63 |
Metastatic |
No prior chemotherapy |
KRAS, CDKN2A, gBRCA1
|
FOLFIRINOX -- PARP inhibitor vs. placebo (CT) |
0400245_T1 |
M |
57 |
Metastatic |
No prior chemotherapy |
KRAS |
FOLFIRINOX -- anti-PD-1 mAb/CXCR4 antagonist (CT) -- GA |
0400270_T1 |
F |
66 |
Metastatic |
GA, Cape, 5FU/LV/Nal-Iri, FOLFOX |
KRAS |
anti-PD-1 mAb/anti-GITR mAB agonist (CT) |