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. 2018 Oct 16;18:983. doi: 10.1186/s12885-018-4910-8

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Characterization of CD8 infiltrating cells in NBL before the vaccination. IHC was performed on consecutive sections of FFPE tumor samples that were stained for Tbet, GZMB and PD-1 markers. Examples of immune infiltrating cells with nuclear Tbet, granular cytoplasmic GZMB or membrane PD-1 positive staining are indicated by arrows. Scale bar = 100 μm. For higher magnification, see Additional file 5: Figure S4