Table 2.
Effect of V. adoensis of aqueous, methanol and chloroform leaf extracts on the body weights of P. berghei infected mice
| Test extracts | Dose (mg/kg/day) | Body weight | % Change | |
|---|---|---|---|---|
| Before treatment (D0) | After treatment (D4) | |||
| Aqueous | NC | 28.22 ± 0.42 | 24.66 ± 0.29* | − 12.62a |
| 200 | 27.74 ± 0.21 | 25.66 ± 0.52* | − 7.49b | |
| 400 | 29.08 ± 0.28 | 28.88 ± 0.71 | − 0.68b | |
| 600 | 29.62 ± 0.18 | 28.46 ± 0.49 | − 3.92b | |
| PC | 29.66 ± 0.38 | 28.82 ± 0.16 | − 2.83b | |
| Methanol | NC | 28.92 ± 0.30 | 25.82 ± 0.09* | − 10.72a |
| 200 | 30.60 ± 0.31 | 28.53 ± 0.83 | − 6.76b | |
| 400 | 30.08 ± 0.34 | 29.2 ± 0.68 | − 2.93b | |
| 600 | 28.5 ± 0.36 | 28.2 ± 0.40 | − 1.05b | |
| PC | 27.27 ± 0.26 | 27.12 ± 0.24 | − 0.55b | |
| Chloroform | NC | 26.58 ± 0.47 | 22.72 ± 0.27* | − 14.52a |
| 200 | 51.67 ± 0.25 | 51.02 ± 0.46 | − 1.26b | |
| 400 | 52.3 ± 0.36 | 52.12 ± 0.33 | − 0.34b | |
| 600 | 53.16 ± 0.63 | 53.13 ± 0.64 | − 0.06b | |
| PC | 51.42 ± 0.35 | 52.08 ± 0.55 | 1.28b | |
Values are presented as Mean ± SEM
NC, negative control (0.2 ml of respective vehicle); PC, positive control (0.2 ml of CQ)
* There was significant change between D0 and D4 (P < 0.05)
a,bValues in the same column followed by the same letter do not differ significantly (P > 0.05)