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. 2018 Oct 17;18:160. doi: 10.1186/s12935-018-0662-4

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Expressions of CLDNs family members in OS cell lines and osteoblast line. a Detection of the expression of CLDNs family members in OS cell lines and osteoblast line by Realtime-PCR. b Detection of CLDN2 expression in OS cell lines and osteoblast line by Western blotting. c The corresponding statistical analysis of protein expression. d The protein expression of CLDN2 in OS tissues and normal bone tissues. Normalized with β-actin, the *P < 0.05, **P < 0.01 compared with the hFOB.1.19 group