Table 1.
Expression of CLDN2 and clinicopathological characteristics in OS patients
| Item | N | CLDN2 (high) | CLDN2-negative (low) | P |
|---|---|---|---|---|
| Tumor tissue | 27 | 9 | 18 | < 0.001* |
| Normal | 10 | 8 | 2 | |
| Age (years) | ||||
| ≤ 19 | 15 | 5 | 10 | 0.871 |
| > 19 | 12 | 4 | 7 | |
| Gender | ||||
| Male | 16 | 5 | 11 | 1.000 |
| Female | 11 | 4 | 7 | |
| Stage | ||||
| IA–IIA | 10 | 3 | 7 | 0.726 |
| IIB–III | 17 | 6 | 11 | |
| Response to chemotherapy | ||||
| Poor | 9 | 2 | 7 | 0.642 |
| Good | 7 | 2 | 5 | |
| NA (n = 8) | 11 | |||
| Pulmonary metastasis | ||||
| + | 21 | 6 | 15 | < 0.001* |
| − | 6 | 3 | 3 | |
NA not available
* Statistical significance was found with the Chi-square test/Chi-square goodness-of-fit test