Table 3.

Comparative semi‐quantitative analysis of PrP‐plaques visualized by 3F4‐immunohistochemistry among the three cases

	Case 1 (45 yo, F)	Case 2 (56 yo, F)	Case 3 (49 yo, M)
Brain weight (g)	1,060 g	975 g	1,560 g
Disease duration (years)	6	12	2
Cerebral cortex
Frontal
S	+	++	‐
M	++	+++	+
D	+++	+++	+++
Temporal
S	+	++	‐
M	++	+++	+
D	+++	+++	++
Parietal
S	+	NA	+
M	++	NA	++
D	+++	NA	+++
Occipital
S	+	+	+
M	++	++	++
D	+++	+++	+++
Basal ganglia	+++	+++	+++
Hippocampus	+++	+++	‐
Thalamus	++	++	+
Cerebellar cortex	‐	+++	–

yo, years old; M, male; F, female; NA, not available; S, superficial; M, middle; D, deep; –, none; +, sparse; ++, moderate; +++, frequent.