Figure 3.

In vitro drug-releasing properties. A) In vitro release profiles from the composite hydrogels with varying clay contents in cPBS medium of pH 7.4. B) Quantification of burst release measured by release within first 24 hours. C) Release profiles of composite hydrogels with 6% clay in release medium of varying pH. The ANOVA test was performed on the total amount of released drug. D) Zeta potentials of the clay nanoparticles at different pH. Data represents the mean ±SD; N=3 per group. P values were determined by ANOVA test; *P≤0.05; **P≤0.01; ***P≤0.001; ****P≤0.0001.