Table 1.
Description of Included Studies
| Initiative | Location (Health care Provision Type) | Duration of Intervention | Intervention, n | Control, n | Age (SD) | DUP Definition | FEP Definition | Intervention Type (Target) |
|---|---|---|---|---|---|---|---|---|
| CIEIS29 | London, UK (Semashko) | 12 months | 104 | 66 | 22.4 (6.3) | Retrospective, clinical | DSM-IV | Community intervention (Community workers— non-healthcare) |
| DETECT25 | Dublin, Ireland (Bismarck) | 78 months | 172 | 151 | 26.2 (IQR: 20.9, 36.0) | Retrospective, clinical | DSM-IV | Multifocus intervention (GPs, general public, universities) |
| EASY/JCEP26 | Hong Kong (Semashko) | 12 months | 479 | 122 | 31.6 (8.4) | Retrospective, clinical | DSM-IV | Community intervention (general public) |
| EDEN28 | Birmingham, UK (Semashko) | 18 months | 77 | 74 | 30.9 | Retrospective, clinical | DSM-IV | Community intervention (general public, patients) |
| EPIP17 | Singapore (Bismarck) | 2 years | 287 | 107 | 25.4 (8.5) | Retrospective, clinical | DSM-III-R | Multifocus intervention (GPs, general public, patients, patients’ families) |
| EPPIC18 | Melbourne, Australia (Bismarck) | 8 months | 51 | 51 | 22.4 (3.8) | Retrospective, clinical | DSM-III-R | Standalone FEP service |
| EPPIC24 | Melbourne, Australia (Bismarck) | 12 months | 40 | 58 | 22.2 (3.4) | Retrospective, clinical | DSM-IV | Multifocus intervention (GPs, secondary schools) |
| IMAGES30 | Jujuy, Argentina (Bismarck) | 6 years | 53 | 53 | 30.7 (11.1) | Retrospective, clinical | DSM-IV/ ICD-10 | Healthcare professional training (health workers) |
| LEOCAT21 | London, UK (Semashko) | 27 months | 36 | 35 | 23.9 (5.27) | Retrospective, psychometric | DSM-IV | Healthcare professional training (GPs) |
| OASIS20 | London, UK (Semashko) | 5 years | 43 | 147 | 24.0 (5.5) | Prospective, psychometric | DSM-IV | Standalone ARMS service |
| PAE-TPI46 | Barcelona, Spain (Semashko) | 15 months | 133 | 58 | - | Retrospective, clinical | DSM-IV | Standalone FEP service |
| PEPP50 | Ontario, Canada (Semashko) | 2 years | 85 | 84 | 25.0 (7.8) | Retrospective, clinical | DSM-IV | Multifocus intervention (GPs, general public, high school students, university students, patients’ families) |
| PEPP27 | Ontario, Canada (Semashko) | 42 months | 145 | 132 | 24.3 (4.0) | Retrospective, clinical | DSM-IV | Healthcare professional training (GPs) |
| REDIRECT51 | Birmingham, UK (Semashko) | 30 months | 65 | 58 | 22.7 (3.7) | Retrospective, clinical | ICD-10 | Healthcare professional training (GPs) |
| STEP45 | USA (market-based) | 18 months | 53 | 22 | — | Retrospective, psychometric | DSM-IV | Multifocus intervention (secondary schools, GPs, acute clinical care providers, community agencies) |
| TIPS15 | Rogaland County, Norway (Bismarck) | 4 years | 141 | 140 | 28.6 (9.1) | Retrospective, psychometric | DSM-IV | Multifocus intervention (GPs, general public, healthcare workers) |
Note: FEP, first-episode psychosis; DUP, duration of untreated psychosis; DSM, diagnostic and statistical manual of mental disorders; ICD, International Statistical Classification of Diseases and Related Health Problems.