Table 2.

Unadjusted and Adjusted Associations Between Cannabis Use (Any and Weekly) and Hypomania Symptoms at 22–23 Years

Cannabis Variable	Hypomania Outcome
	Model A	Model B, Adjustment for Psychotic Symptoms and Depression	Model C, Plus Adjustment for Other Drug and Hazardous Alcohol Use	Model D, Plus Adjustment for Gender, Family Adversity, and Early Childhood Physical or Sexual Abuse
Any cannabis use	(N = 1959)	(N = 1818)	(N = 1658)	(N = 1658)
No	[reference]	[reference]	[reference]	[reference]
Yes	1.64 (1.37, 1.96)	1.66 (1.38, 1.99)	1.44 (1.15, 1.79)	1.42 (1.14, 1.77)
Weekly cannabis use	(N = 1956)	(N = 1816)	(N = 1656)	(N = 1656)
No (infrequent cannabis use, ie, less than weekly)	[reference]	[reference]	[reference]	[reference]
Yes (at least 2–3 times weekly)	2.80 (2.02, 3.88)	2.58 (1.85, 3.60)	2.24 (1.52, 3.31)	2.21 (1.49, 3.28)

Note: All analyses weighted for gender, birthweight, family adversity, and maternal shouting; Model A: unadjusted associations; Model B: associations adjusted for psychotic symptoms and depression; Model C: associations adjusted for psychotic symptoms, depression, other drug use, and hazardous alcohol use; Model D: associations adjusted for psychotic symptoms and depression, other drug use, hazardous alcohol use, gender, family adversity, and childhood abuse. Bold signifies the positive results clear in the table.