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. Author manuscript; available in PMC: 2018 Oct 17.
Published in final edited form as: Cell Rep. 2018 Sep 25;24(13):3367–3373.e4. doi: 10.1016/j.celrep.2018.08.075

Figure 1. NK-Cell-Depleted Mice Have Larger TFH and GC B Cell Populations Relative to NK-Cell-Replete Controls.

Figure 1.

(A) Frequency of GC TFH (CD4+ CD44hi CXCR5+ PD-1hi) cells in control or α-NK1.1 mice twelve days post-immunization with NP-KLH in alum.

(B) Total number of GC TFH day 12 post-immunization in spleen.

(C and D) Frequency of germinal center B (CD19+B220+Fas+GL-7+) cells in the spleens of control or α-NK1.1 mice day 12 post-immunization (C) and total number of GC B cells in spleen day 12 post-immunization (D). Data were analyzed via Student’s t test; n = 9–10 mice/group. Experiments were repeated 3 times.