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. 2018 Oct 17;13(10):e0204731. doi: 10.1371/journal.pone.0204731

Table 1. The effect of maternal separation on the isolated pancreatic islets insulin content and insulin secretion as a percentage of insulin content in the presence of different concentrations of glucose in young adult male rats.


Insulin Content (ng/mg Protein) Insulin Output/Insulin Content (%)
Medium Glucose (mM) Medium Glucose (mM)
Group 0 5.6 16.7 0 5.6 16.7
Non-STR 23.65±9.41 92.05±9.41 105.88±9.41 71.31±5.14 83.71±5.14 92.67±5.14
STR 23.06±9.41 14.50 ±9.41**** 88.61 ±9.41 68.91±5.14 71.17±5.14 92.68±5.14

Values are expressed as the mean ± SEM in six young adult male rats (two groups of ten islets for each concentration of glucose in each animal); STR: Stress,

****P<0.0001 vs. non-STR of the same glucose concentration.