Table 1. The effect of maternal separation on the isolated pancreatic islets insulin content and insulin secretion as a percentage of insulin content in the presence of different concentrations of glucose in young adult male rats.
Insulin Content (ng/mg Protein) | Insulin Output/Insulin Content (%) | |||||
---|---|---|---|---|---|---|
Medium Glucose (mM) | Medium Glucose (mM) | |||||
Group | 0 | 5.6 | 16.7 | 0 | 5.6 | 16.7 |
Non-STR | 23.65±9.41 | 92.05±9.41 | 105.88±9.41 | 71.31±5.14 | 83.71±5.14 | 92.67±5.14 |
STR | 23.06±9.41 | 14.50 ±9.41**** | 88.61 ±9.41 | 68.91±5.14 | 71.17±5.14 | 92.68±5.14 |
Values are expressed as the mean ± SEM in six young adult male rats (two groups of ten islets for each concentration of glucose in each animal); STR: Stress,
****P<0.0001 vs. non-STR of the same glucose concentration.