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. 2018 Oct 17;13(10):e0205965. doi: 10.1371/journal.pone.0205965

Table 1. Clinical characteristics of the no leakage and leakage groups.

No leakage group (n = 115) Leakage group (n = 152)
Sex, no. female/male 42/73 70/82
Age, year, median (IQR) 35 (24–47) 32.5 (25–43.75)
BMI, kg/m2, median (IQR) 24.22 (22.83–27.88) 24.60 (23.04–26.62)
Blood pressure, critical phase
SBP, mmHg, median (IQR) 110 (110–120) 110 (110–120)
DBP, mmHg, median (IQR) 80 (70–80) 73 (70–80)
AST level, febrile phase, U/L, median (IQR) 41 (27–65) 49 (33–89.50)a,*
ALT level, febrile phase, U/L, median (IQR) 54 (35–84) 56 (37–88.75)
AST level, critical phase, U/L, median (IQR) 81 (43–133) 152.50 (94.25–279.5) a,*
ALT level, critical phase, U/L, median (IQR) 83 (51–133) 119 (69–218.25) a,*
Hemoconcentration, %, median (IQR) 10.62 (7.71–13.85) 16.92 (11.25–23.09) a,*
Lowest platelet count, × 1,000/μL, median (IQR) 69 (34–101) 19 (12–33.75) a,*
Albumin level, g/dL, median (IQR) 3.5 (3.2–3.7) 3.1 (2.9–3.3) a,*
Absence of NAFLD, n (%) 53 (38.4) 85 (61.6)
Presence of NAFLD, n (%) 62 (48.1) 67 (51.9)
Severe dengue, n (%) 0 8 (5.26)b,*
AST or ALT ≥1000 U/L, n (%) 0 3 (1.97)
Shock, n (%) 0 2 (1.31)
Respiratory distress, n (%) 0 1 (0.66)
Acute kidney injury, n (%) 0 1 (0.66)
Multiple organ failure, n (%) 0 1 (0.66)
LOS, days, median (IQR) 5 (4–6) 6 (5–7) a,*

Abbreviations: BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; AST, aspartate aminotransferase; ALT, alanine aminotransferase; IQR, interquartile range; NAFLD, nonalcoholic fatty liver disease; LOS, length of hospital stay

a The Mann-Whitney test was used to assess differences between the no leakage and leakage groups.

b Fisher’s exact test was used to evaluate associations between the no leakage and leakage groups.

* Significantly different from the no leakage group (p<0.05).