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. 2018 Feb 22;18(3):1582–1591. doi: 10.1021/acs.nanolett.7b03813

Figure 4.

Figure 4

In vivo X-ray computed tomography. (a,b) Representative sagittal images of tumor-bearing mice that were scanned for CT contrast by a micro CT prior to and 24 h post iv injection of IN-ABP HG92, HG90 and respective controls HG31, HG99. Tumors placed on the back of the mice are marked by colored circles. Gold color marks contrast from iodine, gray color marks contrast from bone. (c,d) Differential CT tumor contrast in HU (above background at t = 0), left, and normalized to each tumor mass [80–160 mg], right, of IN-ABP HG92, HG90 and respective control HG31, and HG99. Red bars represent targeted IN-ABPs, blue bars represent control compounds.