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(a) Synthesis of single iodine tagged activity based probe. (b) Three iodide-tagged ABP (7a,b) were synthesized starting from GB111-NH2, which was reacted with succinic anhydride followed by coupling with ethylenediamine core PAMAM-Go and then reacted with SE of either 2,3,5-triiodobenzoic acid or iopanoic acid described in Scheme S1.
