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. Author manuscript; available in PMC: 2018 Oct 17.
Published in final edited form as: Science. 2018 Feb 9;359(6376):698–701. doi: 10.1126/science.aan6398

Fig. 2. Synthetic LARKS construct forms a labile hydrogel.

Fig. 2.

A synthetic LARKS construct with the sequence SYSGYSGDTSYSSYGQSNGPSTGGYG forms a labile hydrogel when dissolved in water at 50mg/ml and left overnight at 4°C. The hydrogel melts upon heating the sample to 60°C for two hours. A bubble (blue arrow) was introduced to the sample to show the difference between the liquid state (bubble rises) and hydrogel state (bubble does not rise). Electron microscopy confirms that fibrils were indeed melted. The hydrogel-forming property of this triple-LARKS sequence suggests that it is the multiple LARKS found in many LCDs that endow their unusual property of forming hydrogels. Scale bars are equal to 200nm.