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. 2018 Aug 14;53(5):1967–1979. doi: 10.3892/ijo.2018.4523

Figure 9.

Figure 9

Effects of caspase inhibition on the viability of cells cotreated with CPT and 3-MA. NSCLC H1299 cells were pretreated with or without the pan-caspase inhibitor Z-VAD-FMK (50 µM) for 2 h, and were then treated with 0.5 µM CPT and 0.5 mM 3-MA for 24 h. Cell viability was determined using the trypan blue exclusion assay. DMSO was used as a vehicle control. 3-MA, 3-methyladenine; CPT, camptothecin; DMSO, dimethyl sulfoxide.