Table X.

Association between SNPs associated with myocardial infarction and intermediate phenotypes.

Gene	SNP	Hypertension	DM	Hyper-TG	Hypo-HDL	Hyper-LDL	CKD	Obesity	Hyperuricemia
PLCB2		rs200787930	C/T	0.0004	0.0026	0.5013	<0.0001	<0.0001	<0.0001	0.0482	0.7764
CXCL8	rs188378669	G/T	0.0007	0.0039	0.8922	<0.0001	<0.0001	<0.0001	0.0259	0.9412
MARCH1	rs61734696	G/T	0.0002	0.0013	0.5876	<0.0001	<0.0001	<0.0001	0.0381	0.7835
VPS33B	rs199921354	C/T	0.0006	0.0026	0.5939	<0.0001	<0.0001	<0.0001	0.0398	0.9038
TMOD4	rs115287176	G/A	0.0006	0.0073	0.9087	<0.0001	<0.0001	<0.0001	0.0578	0.8457
COL6A3	rs146092501 C	/T	0.0004	0.0058	0.8385	<0.0001	<0.0001	<0.0001	0.0459	0.8305
ZNF77	rs146879198	G/A	0.0014	0.0053	0.8625	<0.0001	<0.0001	<0.0001	0.0245	0.9643
ADGRL3	rs192210727	G/T	0.0106	0.0262	0.6918	<0.0001	<0.0001	<0.0001	0.0501	0.5669
ALDH2	rs671	G/A	0.0017	0.0231	0.0253	<0.0001	0.0002	0.0297	0.0479	<0.0001
ACAD10	rs11066015	G/A	0.0014	0.0300	0.0261	<0.0001	0.0002	0.0376	0.0578	<0.0001
BRAP	rs3782886	A/G	0.0012	0.0675	0.0233	<0.0001	0.0008	0.0329	0.0548	<0.0001
HECTD4	rs11066280	T/A	0.0052	0.2161	0.0093	<0.0001	0.0002	0.0172	0.1293	<0.0001
HECTD4	rs2074356	C/T	0.0245	0.2148	0.0042	<0.0001	0.0003	0.0218	0.2238	<0.0001
OR52E4	rs11823828	T/G	0.0429	<0.0001	0.0917	0.2341	0.8312	0.0161	0.0768	0.1053
	rs12229654	T/G	0.0200	0.4309	0.0996	<0.0001	0.0290	0.0633	0.2134	<0.0001
NAA25	rs12231744	C/T	0.0913	0.5214	0.0151	0.0002	0.2175	0.8586	0.3543	0.0055
ATXN2	rs7969300	T/C	0.0368	0.6341	0.0001	0.0005	0.7189	0.3631	0.3155	0.0047
GOSR2	rs1052586	T/C	0.5175	0.0843	0.3162	0.0718	0.1779	0.6525	0.4307	0.5766
TCHP	rs74416240	G/A	0.4244	0.0279	0.0630	0.0594	0.0142	0.0037	0.3409	0.1148
GIT2	rs925368	A/G	0.3492	0.0515	0.0337	0.0873	0.0105	0.0020	0.4399	0.0998
	rs2523644	A/G	0.4464	0.2581	0.5651	0.0797	0.0674	0.0397	0.4203	0.3215
OAS3	rs2072134	C/T	0.6477	0.0936	0.1902	0.0004	0.0030	0.1862	0.2580	0.0185
CCDC63	rs10774610	T/C	0.3573	0.2133	0.2623	0.0030	0.0102	0.0055	0.5909	<0.0001
	rs2596548	G/T	0.2749	0.0268	0.2615	0.2138	0.3223	0.0751	0.9065	0.2475
CCDC63	rs10849915	T/C	0.3386	0.2256	0.2891	0.0025	0.0135	0.0060	0.5869	<0.0001

Data are P-values. The association between genotypes of each SNP and intermediate phenotypes was examined with Pearson's χ² test. Based on Bonferroni's correction, P<0.0003 (0.05/200) were considered statistically significant and are shown in bold. SNP, single nucleotide polymorphism; DM, diabetes mellitus; hyper-TG, hypertriglyceridemia; hypo-HDL, hypo-high density lipoprotein-cholesterolemia; hyper-LDL, hyper-low density lipoprotein-cholesterolemia; CKD, chronic kidney disease.