Table XII.

Association between SNPs associated with chronic kidney disease and the serum concentration of creatinine and eGFR.

Gene	SNP		Serum creatinine (µmol/l)			P-value	eGFR (ml min−1 1.73 m−2)			P-value
COL6A5	rs200982668	G/A	GG	GA		0.0281	GG	GA		<0.0001
			93.6±138.5	61.8±34.4			79.3±32.9	95.2±20.2
MARCH1	rs61734696	G/T	GG	GT		0.0352	GG	GT		<0.0001
			93.5±138.3	62.4±35.0			79.3±32.9	94.7±20.3
MUC17	rs78010183	A/T	AA	AT		0.0068	AA	AT		<0.0001
			93.8±139.0	59.2±18.8			79.4±33.0	93.0±19.9
MOB3C	rs139537100 C	/T	CC	CT		0.0374	CC	CT		<0.0001
			93.5±138.4	62.4±35.5			79.3±32.9	94.9±20.8
PLCB2	rs200787930 C	/T	CC	CT		0.0380	CC	CT		<0.0001
			93.5±138.3	62.5±35.4			79.3±32.9	94.8±20.8
CXCL8	rs188378669	G/T	GG	GT		0.0397	GG	GT		<0.0001
			93.5±138.3	62.6±35.6			79.3±32.9	95.0±20.9
VPS33B	rs199921354 C	/T	CC	CT		0.0406	CC	CT		<0.0001
			93.5±138.4	62.6±35.8			79.3±32.9	94.8±21.1
TMOD4	rs115287176	G/A	GG	GA		0.0426	GG	GA		<0.0001
			93.4±138.2	62.8±35.8			79.4±32.9	94.6±20.9
ADGRL3	rs192210727	G/T	GG	GT	TT	0.1294	GG	GT	TT	0.0002
			93.2±137.5	63.0±35.8	64.5		79.3±32.9	94.4±21.4	94.3
ZNF77	rs146879198	G/A	GG	GA		0.0491	GG	GA		<0.0001
			93.4±138.1	63.1±36.4			79.4±32.9	94.3±21.1
COL6A3	rs146092501 C	/T	CC	CT		0.0466	CC	CT		<0.0001
			93.4±138.2	62.8±36.4			79.4±32.9	94.6±21.2

Data are presented as the mean ± standard deviation and were compared among genotypes by one-way analysis of variance. Based on Bonferroni's correction, P<0.0023 (0.05/22) was considered statistically significant and are shown in bold. SNP, single nucleotide polymorphism; eGFR, estimated glomerular filtration rate.