Table XIV.
Association between genes, chromosomal loci, and SNPs associated with hypertension in the present study and previously examined cardiovascular disease-related phenotypes.
| Gene/chr. locus | SNP | Chr. | Position | Previously examined phenotypes |
|---|---|---|---|---|
| MOB3C | rs139537100 | 1 | 46615006 | None |
| TMOD4 | rs115287176 | 1 | 151170961 | None |
| COL6A3 | rs146092501 | 2 | 237371861 | None |
| COL6A5 | rs200982668 | 3 | 130470894 | None |
| CXCL8 | rs188378669 | 4 | 73741568 | Total cholesterol (23063622) |
| MARCH1 | rs61734696 | 4 | 164197303 | Adiponectin concentrations (20887962) |
| NFKBIL1 | rs2071593 | 6 | 31545022 | Total cholesterol (20686565) |
| 6p21.3 | rs769177 | 6 | 31579834 | Total cholesterol (20686565), triglycerides (20686565), CAD (21971053) |
| NCR3 | rs2515920 | 6 | 31594838 | Total cholesterol (20686565) |
| PLCB2 | rs200787930 | 15 | 40289298 | Triglycerides (23063622) |
| VPS33B | rs199921354 | 15 | 91013841 | Type 2 diabetes (22885922) |
Data were obtained from the Genome-Wide Repository of Associations Between SNPs and Phenotypes Search database (https://grasp.nhlbi.nih.gov/Search.aspx) with a P<1.0×10−6. Numbers in parentheses are PubMed IDs. SNP, single nucleotide polymorphism; Chr., chromosome; CAD, coronary artery disease.