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. 2018 Aug 14;42(5):2650–2664. doi: 10.3892/ijmm.2018.3826

Table III.

Top 10 significantly enriched GO terms in three categories by genes co-expressed with homeobox A11.

Category/term Count P-value FDR
Biological process
 GO:0048598-Embryonic morphogenesis 44 6.79×10−10 0.000001
 GO:0001501-Skeletal system development 45 7.03×10−10 0.000001
 GO:0007389-Pattern specification process 37 4.66×10−8 0.000084
 GO:0048754-Branching morphogenesis of a tube 17 7.79×10−8 0.000140
 GO:0048568-Embryonic organ development 28 1.02×10−7 0.000183
 GO:0048706-Embryonic skeletal system development 18 1.71×10−7 0.000306
 GO:0048704-Embryonic skeletal system morphogenesis 15 5.22×10−7 0.000938
 GO:0001763-Morphogenesis of a branching structure 17 5.32×10−7 0.000955
 GO:0001944-Vasculature development 33 9.30×10−7 0.001669
 GO:0051270-Regulation of cell motion 28 1.08×10−6 0.001945
Cellular component
 GO:0044421-Extracellular region part 79 7.0×10−6 0.009522
 GO:0005912-Adherens junction 23 7.0×10−6 0.010227
 GO:0005925-Rocal adhesion 18 9.0×10−6 0.013065
 GO:0070161-Anchoring junction 24 1.2×10−6 0.017438
 GO:0005924-Cell-substrate adherens junction 18 1.6×10−6 0.022116
 GO:0015629-Actin cytoskeleton 31 2.5×10−6 0.035229
 GO:0030055-Cell-substrate junction 18 3.2×10−6 0.046211
 GO:0031012-Extracellular matrix 35 9.3×10−6 0.133109
 GO:0005856-Cytoskeleton 99 1.1×10−5 0.161576
 GO:0043235-Receptor complex 16 5.6×10−5 0.798459
Molecular function
 GO:0003779-Actin binding 38 2.0×10−6 0.002752
 GO:0008092-Cytoskeletal protein binding 49 8.0×10−6 0.012857
 GO:0019838-Growth factor binding 18 1.3×10−6 0.020705
 GO:0005520-Insulin-like growth factor binding 9 1.7×10−6 0.026080
 GO:0005509-Calcium ion binding 72 8.8×10−6 0.135240
 GO:0043565-Sequence-specific DNA binding 51 2.3×10−5 0.357942
 GO:0003700-Transcription factor activity 71 8.2×10−5 1.256619
 GO:0004970-Ionotropic glutamate receptor activity 6 1.4×10−4 2.177531
 GO:0005234-Extracellular-glutamate-gated ion channel activity 6 1.8×10−4 2.828013
 GO:0019899-Enzyme binding 42 2.2×10−4 3.271727

GO, Gene Ontology; FDR, false discovery rate.