Table I.
Association between ISL1 expression and clinicopathological parameters of patients with breast cancer.
| Clinicopathological parameters | N | ISL1 (fold-change) | P-value |
|---|---|---|---|
| Age, years | 0.64 | ||
| <35 | 9 | 3.15±1.35 | |
| ≥35 | 26 | 3.37±1.21 | |
| Tumor size, cm | 0.71 | ||
| <4 | 17 | 3.39±1.25 | |
| ≥4 | 18 | 3.24±1.97 | |
| Histological grade | 0.60 | ||
| Well/intermediate differentiation | 14 | 3.45±1.11 | |
| Poor differentiation | 21 | 3.22±1.67 | |
| Invasion depth | 0.36 | ||
| Tis-T2 | 22 | 3.17±1.37 | |
| T3-T4 | 13 | 3.56±1.77 | |
| Lymph node metastasis | 0.04a | ||
| N0 | 11 | 2.71±0.85 | |
| N1-N3 | 24 | 3.59±1.24 | |
| Distant metastasis | 0.04a | ||
| M0 | 29 | 3.13±1.25 | |
| M1 | 6 | 4.22±1.49 |
a
P<0.05. Tis, tumor in situ. ISL1, Islet 1.