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Changes in metabolome profiles in the cholestasis rats with or without melatonin treatment. The levels of (A) 5-aminopentanoate, (B) 5-methoxy-tryptamine, (C) L-tryptophan, (D) threonine, (E) glutathione, (F) L-methionine, and (G) indolelactate are displayed. The squares indicate the mean value of expression. **P<0.01 vs. control group; ^P<0.05 and ^^P<0.01 vs. cholestasis model group.
