Figure 6.

PTE is a safe drug for the treatment of MM. (A) Liver damage markers, including ALT, AST, ALP and TBIL were measured in serum samples from NOD/SCID mice treated with 5% DMSO or PTE with an automatic biochemical analyzer. (B) Kidney function markers BUN and Scr were measured in serum samples from NOD/SCID mice treated with 5% DMSO or PTE by an automatic biochemical analyzer. (C) Cardiac injury markers cTnT and CK-MB were measured with an ELISA kit. The values are expressed as means ± standard deviation. PTE, pterostilbene; MM, multiple myeloma; ALT, alanine aminotransferase; AST, aspartate amino transferase; ALP, alkaline phosphatase; TBIL, total bilirubin; DMSO, dimethyl sulfoxide; BUN, urea nitrogen; Scr, serum creatinine; cTnT, cardiac troponins T; CK-MB, creatine kinase-MB.