Figure 5.
Effects of 1,5-diCQA on the transcriptional TYR family and MITF. B16 cells were treated with 1,5-diCQA at 5, 50 and 100 µM for 24 h. The mRNA levels of TYR family and MITF were detected using reverse transcription quantitative polymerase chain reaction. **P<0.01 and ***P<0.001 vs. untreated control. TYR, tyrosinase; MITF, microphthalmia-associated transcription factor; 1,5-diCQA, 1,5-dicaffeoylquinic acid.