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Effects of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase and c-Jun N-terminal kinase inhibitors on 1,5-diCQA-induced MITF expression. B16 cells were pre-incubated with (A) SB203580 (10 µM), (B) PD98059 (1 µM) or (C) SP600125 (10 µM) for 2 h prior to the addition of 1,5-diCQA (100 µM), and then incubated for 48 h. MITF expression was measured by western blot analysis.
