Table II.
A list of metabolites that were significantly different (P < 0.05) between patients with OSCC and OD
| Compound Name | Fold induction | p-value |
|---|---|---|
| Pyruvate+Oxalacetic acid | 0.76 | 0.0039 |
| Lactic acid | 0.69 | <0.0001 |
| Glycolic acid | 0.84 | 0.0120 |
| Alanine | 0.77 | 0.0016 |
| Oxalate | 0.65 | 0.0003 |
| Sarcosine | 0.56 | 0.0001 |
| 2-Aminoisobutyrate | 1.39 | 0.0015 |
| 3-Hydroxyisovaleric acid | 1.74 | 0.0085 |
| Urea | 0.25 | 0.0016 |
| Benzoic acid | 0.58 | <0.0001 |
| Oxamic acid | 1.12 | 0.0496 |
| Glycerol | 1.40 | 0.0388 |
| Phosphate | 0.90 | 0.0205 |
| Nonanoic acid | 2.88 | <0.0001 |
| β-Alanine | 0.61 | 0.0001 |
| Methionine | 1.45 | 0.0254 |
| Creatinine | 1.83 | 0.0369 |
| Phenylalanine | 1.14 | 0.0289 |
| Threo-β-Hydroxyaspartic acid | 0.66 | 0.0044 |
| Lauric acid | 1.44 | 0.0007 |
| Ribose | 0.78 | 0.0193 |
| Phthalic acid | 0.62 | 0.0001 |
| Methoxy-4-Hydroxyphenylacetate | 0.86 | 0.0400 |
| O-Phosphoethanolamine | 0.77 | 0.0029 |
| Glycyl-Glycine | 0.72 | <0.0001 |
| Citric acid+Isocitric acid | 1.23 | 0.0075 |
| Ornithine | 0.78 | 0.0026 |
| Hypoxanthine | 2.22 | 0.0010 |
| Tagatose | 0.78 | 0.0408 |
| Mannose | 1.19 | 0.0246 |
| 5-Dehydroquinic acid | 0.64 | 0.0002 |
| Glucose | 0.59 | <0.0001 |
| Sebacic acid | 0.58 | <0.0001 |
| Galactose | 0.57 | <0.0001 |
| Lysine | 0.82 | 0.0065 |
| Galactosamine | 0.59 | 0.0004 |
| Glucuronate | 0.80 | 0.0069 |
| Ascorbic acid | 0.76 | 0.0068 |
| Cysteic acid | 0.84 | 0.0233 |
| 1-Hexadecanol | 1.59 | 0.0178 |
| Glucarate | 0.67 | <0.0001 |
| Dopa | 0.76 | 0.0063 |
| Elaidic acid | 1.44 | 0.0352 |
| Cysteine+Cystine | 2.06 | <0.0001 |
The values are shown as fold induction values (the peak intensity of patients with OSCC divided by that of patients with OD). If the fold induction shows lower than 1, metabolite level is lower in patients with OSCC than patients with OD. P values were calculated with the Student’s t-test.