Figure 2.
A. Progression-free survival (PFS) according to IGHV-MS and ZAP70 expression. B. PFS from the 3-month landmark according to minimal residual disease (MRD) level in bone marrow (BM) after course 3 in the whole patient cohort. C. PFS analysis from the 3-month landmark in all patients who achieved undetectable MRD (U-MRD) status in BM after course 3, according to number of total FCR courses received. D. PFS analysis from the 3-month landmark in mutated-IGHV patients who achieved U-MRD status in BM after course 3, according to number of FCR courses received. E. PFS from the 6-month landmark according to IGHV-MS and MRD positive vs undetectable. F. PFS from the 6-month landmark according to timing of achieving U-MRD status. U-MRD @EOT denotes that the patient was MRD-positive after course 3 and had U-MRD at the end of therapy (EOT).