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. 2018 Jan 8;50(4):1304–1315. doi: 10.4143/crt.2017.463

Table 5.

Late toxicities in patients treated with IC+CCRT versus CCRT

Late toxicity IC+CCRT (n=38) CCRT (n=33) p-valuea)
Xerostomiab) 4 (10.5) 7 (21.2) 0.215
Hearing lossb) 14 (36.8) 10 (30.3) 0.561
Skin dystrophy 1 (2.6) 1 (3.0) > 0.999
Neck fibrosis 9 (23.7) 6 (18.2) 0.571
Trismusb) 3 (8.1) 2 (6.1) > 0.999
Radiation encephalopathy 1 (2.6) 2 (6.1) 0.901
Cranial nerve palsy 2 (5.2) 4 (12.1) 0.543
Memory impairmentc) 7 (18.4) 5 (15.2) 0.714

Values are presented as number (%). IC, induction chemotherapy; CCRT, concomitant chemoradiotherapy.

a)

p-values were calculated using a chi-square test (or Fisher exact test),

b)

Grade 2-4 toxicities,

c)

Grade 2-3 toxicities.