Table 5.
Characteristics | PedsQL (children’s score) | PedsQL (parents’ score) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Gender distribution | Generic mean (sd) | p-value | Cancer mean (sd) | p-value | Fatigue mean (sd) | p-value | Generic mean (sd) | p-value | Cancer mean (sd) | p-value | Fatigue mean (sd) | p-value |
Female | 65.3(19.3) | 0.92 | 74.7(15.6) | 0.48 | 63.8(15.4) | 0.32 | 59.2 (19.0) | 0.85 | 67.7 (15.8) | 0.43 | 68.2 (15.5) | 0.26 |
Male | 62.2(23.3) | 67.9(22.6) | 56.7(16.8) | 58.8 (16.6) | 63.1 (18.5) | 58.4 (17.3) | ||||||
Age groups | ||||||||||||
2 to 4 years | 65.0 (19.6) | 72.3 (17.4) | 68.1 (17.6) | |||||||||
5 to 12 years | 78.3(11.9) | p < 0.0001 | 85.5(5.9) | p < 0.0001 | 77.9(14.4) | 0.008 | 62.2 (17.1) | 0.14 | 67.9 (14.0) | 0.12 | 70.3 (12.5) | 0.009 |
13 to 18 years | 47.8(15.9) | 56.0(18.1) | 50.0(14.1) | 49.5 (12.4) | 55.2 (17.0) | 49.6 (13.6) | ||||||
Diagnostic groups | ||||||||||||
Leukaemia | 70.4(20.8) | 0.18 | 80.6(22.1) | 0.06 | 65.7(16.7) | 0.009 | 66.6 (19.8) | 0.24 | 75.9 (15.0) 56.1 (15.8) | 0.007 | 73.8 (14.8) | 0.009 |
Solid tumours Central nervous system | 56.4(18.2) | 64.3(19.6) | 51.9(12.0) | 52.3 (14.1) | 59.9 (11.7) | 52.2 (15.2) | ||||||
(CNS) tumours | 75.5(25.8) | 77.4(5.9) | 78.3(5.8) | 55.6 (12.7) | 75.9 (15.0) 56.1 (15.8) | 59.7 (9.4) | ||||||
Treatment modality | ||||||||||||
Chemotherapy | 60.8(21.5) | 0.54 | 70.8(24.3) | 0.54 | 57.3(18.6) | 0.48 | 62.6 (18.3) | 0.37 | 70.4 (18.6) | 0.02 | 65.7 (18.2) | 0.64 |
Combined therapy | 67.2(20.4) | 72.4(14.8) | 64.0(12.7) | 53.5 (15.1) | 57.3 (11.1) | 58.7 (14.5) |
Note: Scores range from 0 to 100; higher scores represent a better HRQOL. Statistics are tests for within group differences and significant differences are highlighted in bold type. sd standard deviation