Table 1.
Baseline characteristics of the early-onset lone AF cohort
| Early-onset lone AF (n = 399) | Control group B (n = 383) | |
|---|---|---|
| Sex, male (n (%)) | 334 (84%) | 257 (67%) |
| Age, years (median (IQR)) | 28 (23–33)a | 71 (66–76)b |
| Height, cm (mean (SD)) | 183 ( ± 8.9) | 172 ( ± 8.8) |
| Weight, kg (mean (SD)) | 91.4 ( ± 49.1) | 77.4 ( ± 14.7) |
| BMI, kg m–2 (mean (SD)) | 27 ( ± 15.5) | 26.4 ( ± 4.9) |
| Smoking, current or previously (n (%)) | 119 (29%) | |
| Alcohol consumption per week (mean (SD)) | 6.0 ( ± 7.2) | |
| Hypertension (n (%)) | 0 (0%) | 246 (64.4%) |
| Diabetes (n (%)) | 0 (0%) | 39 (10.2%) |
| Heart failure (n (%)) | 0 (0%) | 0 (0%) |
| Myocardial infarction (n (%)) | 0 (0%) | 0 (0%) |
| Valvular heart disease (n (%))c | 0 (0%) | 0 (0%) |
| Type of AF (n (%)) | ||
| Paroxysmal | 246 (62%) | |
| Persistent | 126 (32%) | |
| Permanent | 23 (6%) | |
| Family history, self-reported (n (%)) | 157 (39%) |
AF: atrial fibrillation, IQR: interquartile range, SD: standard deviation
aAF onset age
bAge at enrolment
cSevere mitral regurgitation, aortic stenosis, tricuspid regurgitation, or ≥ mild mitral stenosis