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. 2018 Oct 17;8:15312. doi: 10.1038/s41598-018-33478-9

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Upsetr diagram showing benchmarking results for human-chimpanzee DE genes using only iPSC-derived cardiomyocytes collected in this study. Total set sizes are shown on the bottom left, overlaps are shown by links with a filled circle, and the bars above the links shows corresponding size of a specific overlap of DE gene sets. To calculate the proportion of genes that are DE between human and chimpanzee in both heart and iPSC derived cardiomyocytes, overlaps between heart and the target cell type were summed together and divided by the total heart set size. Plot generated using R package Upsetr⁷⁹.