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. 2018 Oct 17;9(11):1062. doi: 10.1038/s41419-018-1084-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Expression alteration of CMG genes in LN-229 cells after MINA53 knockdown for 3 or 5 days. b mRNA expression of the indicated genes in LN-229 and c U-87 MG cells with or without MINA53 knockdown. d ChIP-qPCR analysis of MINA53 enrichment at the promoter regions of CDC45, MCM2, MCM3, or MCM5 in LN-229 cells. e ChIP-qPCR analysis of H3K9me3 enrichment at the promoter regions of CDC45, MCM2, MCM3, or MCM5 in LN-229 cells with or without MINA53 knockdown. All data were analyzed using two-tailed Student’s t-tests. Mean ± s.e.m., n = 3, *P < 0.05, **P < 0.01, ***P < 0.001