Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Oct 17;8:15313. doi: 10.1038/s41598-018-33575-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Therapeutic effect of PD-MSCs in ovariectomized (Ovx) rats. (a) The graph represents the ratio of ovary weight to body weight in Ovx rats transplanted with naïve or spheroid PD-MSCs. (b) E₂ levels in plasma samples from transplanted and non-transplanted rats. (c) Quantification of the expression of human-specific Alu sequences in rat ovary tissues engrafted with naïve PD-MSCs or spheroidal PD-MSCs, as assessed by qRT-PCR. (d) Histological analysis of ovary tissues obtained from Ovx rats transplanted with or without naïve or spheroidal PD-MSCs (left). Quantification of follicles in rat ovary tissues according to PD-MSC transplantation (right). The arrows indicate follicles below 100 µm in size. Scale bar: 20 nm. The data are expressed as the mean ± SE. Symbols: ^*represent a significant difference compared to the NTx group (p < 0.05); ^#represents a significant difference between the Naïve and Spheroid groups (p < 0.05). Abbreviations: Ovx, ovariectomized (unilateral); Con, sham-surgery group; NTx, non-transplanted Ovx model; Naïve, naïve PD-MSC-transplanted group; and Spheroid, spheroid PD-MSC-transplanted group.