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. Author manuscript; available in PMC: 2019 Apr 15.
Published in final edited form as: Nat Chem Biol. 2018 Oct 15;14(11):1051–1058. doi: 10.1038/s41589-018-0143-z

Figure 2. Chloride-Dependent Aggregation of Periplasmic Proteins.

Figure 2.

(a), (b), and (c) 20 μM MBP, 2 μM DppA, and 2 μM OppA, respectively, were incubated in 10 mM HCl, pH 2 containing various NaCl concentrations, and the amount of aggregation was monitored over time via light scattering at 360 nm.

(d)–(f) Addition of a two-fold molar excess of monomeric HdeA completely suppressed the aggregation of all three substrates at the highest chloride concentration tested. These experiments were performed once.