Table 1. Summary of preclinical and clinical studies involving computer-aided diagnosis (CAD) for colonoscopy (experimental studies excluded).
| Reference | Year | Type of CAD | Endoscopic modality | Study design | Subjects | Accuracy 1 |
| Fernandez-Esparrach 3 | 2016 | Automated detection | White-light endoscopy | Retrospective study | 31 lesions | – 2 |
| Takemura 19 | 2010 | Automated classification | Magnifying chromoendoscopy | Retrospective study | 134 images | 99 % |
| Tischendorf 12 | 2010 | Automated classification | Magnifying NBI | Post hoc analysis of prospectively acquired data | 209 lesions | 85 % |
| Gross 13 | 2011 | Automated classification | Magnifying NBI | Post hoc analysis of prospectively acquired data | 434 lesions | 93 % |
| Takemura 14 | 2012 | Automated classification | Magnifying NBI | Retrospective study | 371 lesions | 97 % |
| Kominami 8 | 2016 | Automated classification | Magnifying NBI | Prospective study | 118 lesions | 93 % |
| Mori 20 | 2015 | Automated classification | Endocytoscopy | Retrospective study | 176 lesions | 89 % |
| Mori 9 | 2016 | Automated classification | Endocytoscopy | Retrospective study | 205 lesions | 89 % |
| Misawa 15 | 2016 | Automated classification | Endocytoscopy combined with NBI | Retrospective study | 100 images | 90 % |
| Andre 21 | 2012 | Automated classification | Confocal laser endomicroscopy | Retrospective study | 135 lesions | 90 % |
| Kuiper 22 | 2015 | Automated classification | Laser-induced autofluorescence spectroscopy | Prospective study | 207 lesions | 74 % |
| Rath 10 | 2015 | Automated classification | Laser-induced autofluorescence spectroscopy | Prospective study | 137 lesions | 85 % |
| Aihara 23 | 2013 | Automated classification | Autofluorescence imaging | Prospective study | 102 lesions | – 3 |
| Inomata 24 | 2013 | Automated classification | Autofluorescence imaging | Post hoc analysis of prospectively acquired data | 163 lesions | 83 % |
NBI, narrow-band imaging.
1
Accuracy is expressed in terms of the differentiation of adenomas from non-neoplastic lesions.
2
The sensitivity and specificity were 70.4 % and 72.4 %, respectively. No description regarding accuracy was found in this study.
3
The sensitivity and specificity were 94.2 % and 88.9 %, respectively. No description regarding accuracy was found in this study.