Figure 3.

Ensemble activity correlates of stimulus detection. (A) Schematic depicting two trial outcomes in a visual detection task performed by head-fixed mice. In the left scenario a threshold stimulus is not detected (miss trial), whereas in the right the same stimulus is correctly detected (a rewarded hit trial). (B) Simultaneous 2-photon imaging of V1 neuronal populations in these mice revealed that hit trials were associated with higher response heterogeneity. Adapted under Creative Commons Attribution License from Montijn et al. (2015). (C) Structured ensemble activity was correlated with detection. Top center panel depicts a schematic of a neuronal ensemble showing a recurring stereotypical sequence of activity. Hit trials were associated with higher consistency and temporal precision of these recurring sequential events, compared to miss trials. Adapted with permission from the authors from Montijn et al. (2016b).