Skip to main content
. 2018 Oct 11;12:49. doi: 10.3389/fnsys.2018.00049

Table 1.

Macro- and micro-states.

Macro-states Wakefulness REM sleep Non-REM sleep Anesthesia
N1 N2 N3/SWS Non-dissociative (e.g isoflurane, urethane) Dissociative (e.g., ketamine)
Micro-states Low arousal Local slow oscillations in neocortical circuits Global UP/DOWN states and spindles Global, rhythmic UP/DOWN states, spindles Sporadic UP/DOWN states, gamma bouts
Medium arousal
High arousal/locomotion
Theta/alpha bouts Local UP/DOWN states and spindles

This table presents an overview of the most relevant micro-states, i.e., subdivisions of the generally considered (macro-) brain states, based on the effect they have on how sensory information is processed. We thus here primarily refer to electrophysiological features of neocortical circuits. N1, N2 and N3 corresponds to the different stages of Non-REM sleep, based on Berry et al. (2017); N3, the deepest sleep stage, is also referred to as slow wave sleep (SWS); in rodents, Non-REM is usually not subdivided into stages.