Table 1.
Macro-states | Wakefulness | REM sleep | Non-REM sleep | Anesthesia | |||
---|---|---|---|---|---|---|---|
N1 | N2 | N3/SWS | Non-dissociative (e.g isoflurane, urethane) | Dissociative (e.g., ketamine) | |||
Micro-states | Low arousal | Local slow oscillations in neocortical circuits | Global UP/DOWN states and spindles | Global, rhythmic UP/DOWN states, spindles | Sporadic UP/DOWN states, gamma bouts | ||
Medium arousal High arousal/locomotion |
|||||||
Theta/alpha bouts | Local UP/DOWN states and spindles |
This table presents an overview of the most relevant micro-states, i.e., subdivisions of the generally considered (macro-) brain states, based on the effect they have on how sensory information is processed. We thus here primarily refer to electrophysiological features of neocortical circuits. N1, N2 and N3 corresponds to the different stages of Non-REM sleep, based on Berry et al. (2017); N3, the deepest sleep stage, is also referred to as slow wave sleep (SWS); in rodents, Non-REM is usually not subdivided into stages.